PXD004049 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Quantitative tissue proteomics analysis of primary lung adenocarcinoma |
| Description | In this study, we generated a quantitative lung tissue proteome dataset from lung adenocarcinoma and adjacent normal lung tissues by using iTRAQ labeling combined with 2D-LC-MS/MS. Based on pathway and network analyses, protein expression profiles released in the public Human Protein Atlas database, literature search and novelty, six candidates were selected for validation via immunohistochemistry staining and western blot. Additionally, the clinical and biological significance of two novel candidates, ERO1L and NARS, was further analyzed. Collectively, our results provide a useful biomarker dataset for lung adenocarcinoma diagnosis/prognosis and provide new insights into ERO1L- and NARS- mediated tumorigenesis. |
| HostingRepository | PRIDE |
| AnnounceDate | 2022-03-05 |
| AnnouncementXML | Submission_2022-03-05_00:18:04.730.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Chia-Jung Yu |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | LTQ Orbitrap |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2016-04-25 04:31:54 | ID requested | |
| ⏵ 1 | 2022-03-05 00:18:05 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| curator keyword: Biological, Biomedical |
| submitter keyword: lung cancer |
| adenocarcinoma |
| lymph node metastasis |
| biomarkers |
| ERO1L |
| NARS |
| iTRAQ |
Contact List
| Chia-Jung Yu |
|---|
| contact affiliation | Chang Gung University, Taiwan |
| contact email | yucj1124@mail.cgu.edu.tw |
| lab head | |
| Chia-Jung Yu |
|---|
| contact affiliation | 259 Wen-Hwa 1st Road, Guishan District, Tao-Yuan City, Taiwan |
| contact email | yucj1124@mail.cgu.edu.tw |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/03/PXD004049 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD004049
- Label: PRIDE project
- Name: Quantitative tissue proteomics analysis of primary lung adenocarcinoma
to receive all new ProteomeXchange dataset release announcements!
