PXD004012-2

PXD004012 is an original dataset announced via ProteomeXchange.

Title	Ability of the marine bacterium Pseudomonas fluorescens BA3SM1 to counteract the toxicity of CdSe nanoparticles
Description	CdSe nanoparticles (CdSe NPs) are extensively used in the industry of renewable energies and it is regrettably expectedthat these pollutants will sometime soon appear in marine environmentthrough surface runoff, urban effluents and rivers. Bacteria living in estuarine and coastal sediments will be among the first targets of these new pollutants. The pseudomonads are frequently encountered in these ecosystems. They are involved in several biogeochemical cycles and are known for their high resistance to pollutants. Consequently, this study focussing on the effect of CdSe NPs on the marine strain P. fluorescensBA3SM1 is highly relevant for a number of reasons. First, it aims at improving knowledge about the interactions between bacteria and NPs. This is fundamental to use effectively NPs against pathogenic bacteria. Secondly, this study shows that CdSe NPs of 8 nm in diameter cause a decrease in the secretion of siderophorepyoverdine, a secondary metabolite having a key role in microbial ecology and also employed as a virulence factor in human pathogenic strains such as P. aeruginosa. Consequently, this study highlights that CdSe NPs can have an impact on secondary metabolism of bacteria with environmental and medical implications.
HostingRepository	PRIDE
AnnounceDate	2016-08-17
AnnouncementXML	Submission_2016-08-17_01:13:14.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Lauriane Kuhn
SpeciesList	scientific name: Pseudomonas fluorescens PF5; NCBI TaxID: 1218948;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2016-04-19 05:43:10	ID requested
1	2016-08-17 00:43:49	announced
⏵ 2	2016-08-17 01:13:16	announced	Updated project metadata.

Poirier I, Kuhn L, Demorti, è, re A, Mirvaux B, Hammann P, Chicher J, Caplat C, Pallud M, Bertrand M, Ability of the marine bacterium Pseudomonas fluorescens BA3SM1 to counteract the toxicity of CdSe nanoparticles. J Proteomics, 148():213-27(2016) [pubmed]

curator keyword: Biological

submitter keyword: Marine bacteria

CdSe nanoparticles

Physiological responses

Proteomics

Oxidative stress

Isabelle Poirier
contact affiliation	Institut National des Sciences et Techniques de la Mer Conservatoire National des Arts et Métiers BP324 50103 Cherbourg-Octeville Cedex France
contact email	isabelle.poirier@cnam.fr
lab head
Lauriane Kuhn
contact affiliation	CNRS, IBMC, FRC1589
contact email	l.kuhn@ibmc-cnrs.unistra.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/08/PXD004012

PRIDE project URI

• PRIDE
  1. PXD004012
     1. Label: PRIDE project
     2. Name: Ability of the marine bacterium Pseudomonas fluorescens BA3SM1 to counteract the toxicity of CdSe nanoparticles