⮝ Full datasets listing
PXD003937-1
PXD003937 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Gamma ray irradiation of epithelial carcinoma cells under hypoxic conditions |
| Description | We demonstrate for the first time that under hypoxic conditions, A431 epithelial carcinoma cells exhibit increased viability when exposed to low-dose γ-irradiation, indicating that radiotherapy can promote tumor cell survival when oxygen supply is limited. When assessed using iTRAQ quantitative proteomics and Western blotting, irradiated tumor cells were observed to significantly up-regulate the expression of calcium-binding proteins CALM1, CALU and RCN1, suggesting important roles for these mediators in promoting tumor cell survival during hypoxia. |
| HostingRepository | PRIDE |
| AnnounceDate | 2017-02-27 |
| AnnouncementXML | Submission_2017-02-27_03:37:15.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Siu Kwan Sze |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | iTRAQ4plex-116 reporter+balance reagent acylated residue; monohydroxylated residue; deamidated residue |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2016-04-11 00:51:45 | ID requested | |
| ⏵ 1 | 2017-02-27 03:37:17 | announced | |
| 2 | 2024-10-22 04:04:54 | announced | 2024-10-22: Updated project metadata. |
Publication List
Keyword List
| curator keyword: Biomedical |
| submitter keyword: iTRAQ, cancer, radiotherapy, hypoxia, calcium signaling pathway |
Contact List
| Newman Sze | |
|---|---|
| contact affiliation | NTU |
| contact email | sksze@ntu.edu.sg |
| lab head | |
| Siu Kwan Sze | |
| contact affiliation | Nanyang Technical University |
| contact email | sksze@ntu.edu.sg |
| dataset submitter | |
Full Dataset Link List
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/02/PXD003937 |
| PRIDE project URI |
Repository Record List
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