PXD003702-1

PXD003702 is an original dataset announced via ProteomeXchange.

Title	Aortic Aneurysm iTRAQ HiRIEF proteomics
Description	Conducted proteomics on samples from patients with aortic aneurysm and from non-dilated controls. Furthermore, we investigated both patients with bicuspid aortic valves (BAV) and also the more normal tricuspid aortic valves (TAV). The aim was to elucidate the molecular mechanisms behind the higher propensity of BAV patients to develop aorta dilation and consequent aortic aneurysm.
HostingRepository	PRIDE
AnnounceDate	2016-12-24
AnnouncementXML	Submission_2016-12-23_17:55:44.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Rui Branca
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iTRAQ8plex-116 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2016-02-26 07:05:27	ID requested
⏵ 1	2016-12-23 17:55:45	announced
2	2017-10-24 04:02:02	announced	Updated project metadata.
3	2024-10-22 04:14:14	announced	2024-10-22: Updated project metadata.

Maleki S, Kjellqvist S, Paloschi V, Magn, é J, Branca RM, Du L, Hultenby K, Petrini J, Fuxe J, Lehti, ö J, Franco-Cereceda A, Eriksson P, Bj, ö, rck HM, Dietz HC, Loeys B, Van Laer L, McCallion AS, Mertens L, Mital S, Mohamed SA, Andelfinger G, Mesenchymal state of intimal cells may explain higher propensity to ascending aortic aneurysm in bicuspid aortic valves. Sci Rep, 6():35712(2016) [pubmed]

curator keyword: Biomedical

submitter keyword: human, valves, aneurysm, endothelium, bicuspid, iTRAQ, HiRIEF, Q exactive

Janne Lehtiö
contact affiliation	Dept. Oncology Pathology, Karolinska Institutet, and Science for Life Laboratory, Stockholm, Sweden
contact email	janne.lehtio@ki.se
lab head
Rui Branca
contact affiliation	Clinical Proteomics Unit, Dep. of Oncology-Pathology
contact email	rui.mamede-branca@ki.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/12/PXD003702

PRIDE project URI

• PRIDE
  1. PXD003702
     1. Label: PRIDE project
     2. Name: Aortic Aneurysm iTRAQ HiRIEF proteomics