PXD003284-1

PXD003284 is an original dataset announced via ProteomeXchange.

Title	In-depth proteomics identifies a role for autophagy in controlling ROS-mediated endothelial barrier permeability
Description	We have used in-depth quantitative proteomics to identify processes required for the formation/maintenance of a stable new vessel. To do that we have used SILAC-based proteomics and a simple in vitro humam endothelial cell model that recapitulates vessel formation in vivo.
HostingRepository	PRIDE
AnnounceDate	2016-06-07
AnnouncementXML	Submission_2016-06-07_09:10:39.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sara Zanivan
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetic acid derivatized residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2015-12-07 01:45:37	ID requested
⏵ 1	2016-06-07 09:10:41	announced
2	2024-10-22 04:26:55	announced	2024-10-22: Updated project metadata.

Patella F, Neilson LJ, Athineos D, Erami Z, Anderson KI, Blyth K, Ryan KM, Zanivan S, In-Depth Proteomics Identifies a Role for Autophagy in Controlling Reactive Oxygen Species Mediated Endothelial Permeability. J Proteome Res, 15(7):2187-97(2016) [pubmed]

curator keyword: Biomedical, Biological

submitter keyword: Endothelial cells, SILAC, autophagy, permeability

Sara Zanivan
contact affiliation	CRUK Beatson Institute
contact email	s.zanivan@beatson.gla.ac.uk
lab head
Sara Zanivan
contact affiliation	Vascular Proteomics
contact email	s.zanivan@beatson.gla.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/06/PXD003284

PRIDE project URI

• PRIDE
  1. PXD003284
     1. Label: PRIDE project
     2. Name: In-depth proteomics identifies a role for autophagy in controlling ROS-mediated endothelial barrier permeability