PXD002719-1

PXD002719 is an original dataset announced via ProteomeXchange.

Title	Quantitative proteomic analysis of duck lung tissue during infection of avian influenza
Description	Ducks and wild aquatic birds are the natural reservoirs of avian influenza viruses. However, the host proteome response that causes disease in vivo during infection by the highly pathogenic avian influenza (HPAI) H5N1 virus is still not well understood. In the present study, we compared the proteome response in Muscovy duck lung tissue during 3 day of infection with either a highly virulent or an avirulent H5N1 virus. During infection, proteins involved in immune response of neutrophils and size of cells were increased markedly in the lung by the virulent strain, while the avirulent strain evoked a distinct response, characterized by an increase in proteins involved in cell movement, maturation of dendritic cells, adhesion of phagocytes, and immune response of macrophages.
HostingRepository	PRIDE
AnnounceDate	2022-08-22
AnnouncementXML	Submission_2022-08-22_07:37:26.364.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	ming liao
SpeciesList	scientific name: Anas platyrhynchos (Domestic duck) (Anas boschas); NCBI TaxID: 8839;
ModificationList	iTRAQ4plex-116 reporter+balance reagent acylated residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2015-08-13 01:04:37	ID requested
⏵ 1	2022-08-22 07:37:26	announced

Dataset with its publication pending

curator keyword: Biological, Biomedical

submitter keyword: Duck, Lung tissue, Avian influenza

Ming Liao
contact affiliation	College of Veterinary Medicine, South China Agricultural University, Guangzhou, China
contact email	mliao1968@163.com
lab head
ming liao
contact affiliation	south china agricultural university
contact email	mliao1968@163.com
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD002719
     1. Label: PRIDE project
     2. Name: Quantitative proteomic analysis of duck lung tissue during infection of avian influenza