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PXD002623-2

PXD002623 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleComparative shotgun proteomics of aqueous humor for cataract, glaucoma and pseudoexfoliation eye disorders.
DescriptionThe aim of this work was to characterize proteome of aqueous humor from subjects with various eye conditions such as cataract, glaucoma and pseudoexfoliation syndrome by high-resolution chromate-mass-spectrometry. Twenty nine human aqueous humor samples were processed by shotgun proteomics. Data was searched using MaxQuant package. Totally, 263 protein groups were identified. Label-free quantitation reported some differentially expressed proteins in aqueous humor proteome for the aforementioned eye diseases.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:04:58.040.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterIrina Ilina
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListacetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02015-07-29 02:47:14ID requested
12016-05-23 01:32:10announced
22024-10-22 04:05:02announced2024-10-22: Updated project metadata.
Publication List
Kliuchnikova AA, Samokhina NI, Ilina IY, Karpov DS, Pyatnitskiy MA, Kuznetsova KG, Toropygin IY, Kochergin SA, Alekseev IB, Zgoda VG, Archakov AI, Moshkovskii SA, Human aqueous humor proteome in cataract, glaucoma, and pseudoexfoliation syndrome. Proteomics, 16(13):1938-46(2016) [pubmed]
10.1002/pmic.201500423;
Keyword List
curator keyword: Biomedical
submitter keyword: glaucoma, pseudoexfoliation syndrome, mass spectrometry, aqueous humor, eye disease, cataract,Proteomics
Contact List
Sergey Moshkovskii
contact affiliationLaboratory of Medical Proteomics Department of Personalized Medicine Institute of Biomedical Chemistry Moscow
contact emailsmosh@mail.ru
lab head
Irina Ilina
contact affiliationInstitute of Biomedical Chemistry, Russia
contact emailirinailyina@gmail.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
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