PXD002407-1

PXD002407 is an original dataset announced via ProteomeXchange.

Title	Nanoceria modulates kidney bean proteomic response and compromises its seed quality
Description	There is inadequate understanding of the environmental fate and effects of engineered nanoparticles, including nanoceria. Also, knowledge about the influence of environmental factors on the bioavailability of these particles and resulting impacts on the nutritional quality of crops is limited. Alterations in mineral and macromolecular composition of some grains and fruits under nanoceria exposure have been reported recently; however, the cellular mechanisms associated with the effects are unknown. Here, we show that the impact of nanoceria at 62.5 to 500 mg/kg soil on kidney bean (Phaseolus vulgaris) productivity and seed quality are influenced by soil organic matter content. Seeds obtained from plants exposed to nanoceria at 125 mg/kg showed unique and contrasting response in terms of nutritional quality under varying soil organic matter content. Additionally, quantitative proteomic analysis provides evidence for dose-dependent down-regulation of some major proteins associated with nutrient storage and carbohydrate metabolism, including phaseolin and lectins in the exposed seeds. This study suggests that nCeO2 exposure negatively impacts the nutritional quality of kidney beans. This altered seed quality may have significant implications for food production and human health.
HostingRepository	PRIDE
AnnounceDate	2019-02-21
AnnouncementXML	Submission_2019-02-21_06:47:44.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sanghamitra Majumdar
SpeciesList	scientific name: Phaseolus vulgaris (Kidney bean) (French bean); NCBI TaxID: 3885;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2015-06-22 03:45:09	ID requested
⏵ 1	2019-02-21 06:47:45	announced

Majumdar S, Almeida IC, Arigi EA, Choi H, VerBerkmoes NC, Trujillo-Reyes J, Flores-Margez JP, White JC, Peralta-Videa JR, Gardea-Torresdey JL, Environmental Effects of Nanoceria on Seed Production of Common Bean (Phaseolus vulgaris): A Proteomic Analysis. Environ Sci Technol, 49(22):13283-93(2015) [pubmed]

curator keyword: Biological

submitter keyword: Kidney bean, proteomics, LC MS/MS, nanoceria

Sanghamitra Majumdar
contact affiliation	Research Scientist
contact email	sanghamitra.majumdar@ct.gov
lab head
Sanghamitra Majumdar
contact affiliation	Research Scientist
contact email	majumdarsm@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/02/PXD002407

PRIDE project URI

• PRIDE
  1. PXD002407
     1. Label: PRIDE project
     2. Name: Nanoceria modulates kidney bean proteomic response and compromises its seed quality