PXD002195 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Fly Stress |
Description | Altering the redox state of cysteine residues on protein surfaces is an important response to environmental challenges. While ageing and fasting alter many redox processes, the role of cysteine residues is uncertain. To address this we used a redox proteomic technique, Oxidative Isotope Coded Affinity TAgs (OxICAT), to assess cysteine residue redox changes in Drosophila melanogaster during ageing and fasting. This approach enabled us to simultaneously identify and quantify the redox state of several hundred cysteine residues in vivo. |
HostingRepository | PRIDE |
AnnounceDate | 2018-10-24 |
AnnouncementXML | Submission_2018-10-24_09:48:25.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Andrew James |
SpeciesList | scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227; |
ModificationList | Applied Biosystems cleavable ICAT(TM) heavy |
Instrument | LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2015-05-19 01:03:49 | ID requested | |
⏵ 1 | 2018-10-24 09:48:26 | announced | |
Publication List
Menger KE, James AM, Cochem, é HM, Harbour ME, Chouchani ET, Ding S, Fearnley IM, Partridge L, Murphy MP, Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster. Cell Rep, 11(12):1856-65(2015) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: Drosophila, ROS, starvation, aging |
Contact List
Michael Patrick Murphy |
contact affiliation | MRC Mitochondrial Biology Unit, Cambridge, UK. |
contact email | mpm@mrc-mbu.cam.ac.uk |
lab head | |
Andrew James |
contact affiliation | MRC |
contact email | aj@mrc-mbu.cam.ac.uk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD002195 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD002195
- Label: PRIDE project
- Name: Fly Stress