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PXD001963-2

PXD001963 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia
DescriptionPlasma cell leukemia is a rare and aggressive plasma cell neoplasm that may either originate de novo (primary PCL) or by leukemic transformation of multiple myeloma (MM) to secondary PCL (sPCL). The prognosis of sPCL is very poor, and currently no standard treatment is available due to lack of prospective clinical studies. In an attempt to elucidate factors contributing to transformation, we have performed quantitative proteome profiling of malignant plasma cells collected from the same patient at both the MM and sPCL stages of the disease.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:23:15.929.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAnimesh Sharma
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02015-03-24 07:29:18ID requested
12017-05-02 04:25:06announced
22024-10-22 04:23:24announced2024-10-22: Updated project metadata.
Publication List
Zatula A, Dikic A, Mulder C, Sharma A, V, å, gb, ø CB, Sousa MML, Waage A, Slupphaug G, Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia. Oncotarget, 8(12):19427-19442(2017) [pubmed]
10.18632/oncotarget.14294;
Keyword List
curator keyword: Biomedical
submitter keyword: MM, cell, leukemia, secondary, plasma,PCL, myeloma
Contact List
Geir Slupphaug
contact affiliationPROMEC Core Facility for Proteomics and Metabolomics, Norwegian University of Science and Technology, NTNU, N-7489 Trondheim, Norway
contact emailgeir.slupphaug@ntnu.no
lab head
Animesh Sharma
contact affiliationEngineer at NTNU, Norway
contact emailsharma.animesh@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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