PXD001861-1

PXD001861 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	platelet hyperreactivity project
Description	The aim of this study is to identify candidate genes modulating platelet reactivity in aspirin-treated cardiovascular patients using an integrative network-based approach. Platelet reactivity was assessed in 110 cardiovascular patients treated with aspirin 100mg/d by aggregometry using several agonists. Patients with extreme high or low PR were selected for further analysis. Data derived from quantitative proteomic of platelets and platelet sub-cellular fractions, as well as from transcriptomic analysis were integrated with a network biology approach.
HostingRepository	PRIDE
AnnounceDate	2016-02-22
AnnouncementXML	Submission_2016-02-22_01:45:25.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD001861
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Pierre Fontana
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Velos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2015-03-03 00:37:57	ID requested
⏵ 1	2016-02-22 01:45:26	announced

Publication List

Zufferey A, Ibberson M, Reny JL, Nolli S, Schvartz D, Docquier M, Xenarios I, Sanchez JC, Fontana P, New molecular insights into modulation of platelet reactivity in aspirin-treated patients using a network-based approach. Hum Genet, 135(4):403-414(2016) [pubmed]

Zufferey A, Ibberson M, Reny JL, Nolli S, Schvartz D, Docquier M, Xenarios I, Sanchez JC, Fontana P, New molecular insights into modulation of platelet reactivity in aspirin-treated patients using a network-based approach. Hum Genet, 135(4):403-414(2016) [pubmed]

Keyword List

curator keyword: Biomedical
submitter keyword: Platelets, secretory granules, releasate, cardiovascular patients, network biology, aspirin, high platelet reactivity

curator keyword: Biomedical

submitter keyword: Platelets, secretory granules, releasate, cardiovascular patients, network biology, aspirin, high platelet reactivity

Contact List

Pierre Fontana
contact affiliation	Pierre Fontana, MD, PhD Division of Angiology and Heamostasis University Hospitals of Geneva Rue Gabrielle-Perret-Gentil 4 1205 Geneva Switzerland +41 22 372 97 49
contact email	pierre.fontana@hcuge.ch
lab head
Pierre Fontana
contact affiliation	Angiology and Heamostasis
contact email	pierre.fontana@hcuge.ch
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/02/PXD001861
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/02/PXD001861

PRIDE project URI

Repository Record List

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