PXD001682-1

PXD001682 is an original dataset announced via ProteomeXchange.

Title	BRAF inhibitor resistance in melanoma cell lines
Description	LC-MS/MS analysis of cell lines with induced resistance to BRAF inhibitors
HostingRepository	PRIDE
AnnounceDate	2018-10-19
AnnouncementXML	Submission_2018-10-19_01:16:37.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Maria Pernemalm
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue; iTRAQ8plex-116 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2015-01-15 02:50:55	ID requested
⏵ 1	2018-10-19 01:16:38	announced
2	2024-10-22 04:22:27	announced	2024-10-22: Updated project metadata.

Azimi A, Tuominen R, Costa Svedman F, Caramuta S, Pernemalm M, Frostvik Stolt M, Kanter L, Kharaziha P, Lehti, ö J, Hertzman Johansson C, H, ö, iom V, Hansson J, Egyhazi Brage S, Silencing FLI or targeting CD13/ANPEP lead to dephosphorylation of EPHA2, a mediator of BRAF inhibitor resistance, and induce growth arrest or apoptosis in melanoma cells. Cell Death Dis, 8(8):e3029(2017) [pubmed]

curator keyword: Biomedical

submitter keyword: BRAF resistance, melanoma

Janne Lehtiö
contact affiliation	Janne Lehtiö Science for Life Laboratory/Karolinska Institutet Cancer Proteomics Mass spectrometry Tomtebodavägen 23 171 76 Solna Sweden
contact email	janne.lehtio@ki.se
lab head
Maria Pernemalm
contact affiliation	Clinical Proteomics Unit, Dep. of Oncology-Pathology
contact email	maria.pernemalm@ki.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD001682

PRIDE project URI

• PRIDE
  1. PXD001682
     1. Label: PRIDE project
     2. Name: BRAF inhibitor resistance in melanoma cell lines