PXD001238 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Saccharopolyspora erythraea LC-MSMS |
| Description | Lysine acetylation is a dynamic, reversible post-translational modification that is known to play an important role in regulating the activity of many key enzymes in bacteria. Acetylproteome studies have been performed on some bacteria. However, until now there have been no data on the Actinomycetes, which are the major producers of therapeutic antibiotics. In this study, we investigated the first acetylproteome of the erythromycin-producing Actinomycete Saccharopolyspora erythraea using a high-resolution mass spectrometry-based proteomics approach. Using immune-affinity isolation of acetyl-peptides with an anti-acetyllysine antibody followed by nano-UPLC/MS/MS analysis, we identified 664 unique lysine acetylated sites on 363 proteins. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-11-27 |
| AnnouncementXML | Submission_2025-11-27_05:41:02.785.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | huang dan |
| SpeciesList | scientific name: Saccharopolyspora erythraea (strain NRRL 23338); NCBI TaxID: NEWT:405948; |
| ModificationList | acetylated residue |
| Instrument | LTQ Orbitrap |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2014-08-15 01:33:31 | ID requested | |
| ⏵ 1 | 2025-11-27 05:41:03 | announced | |
Publication List
| Huang D, Li ZH, You D, Zhou Y, Ye BC, Lysine acetylproteome analysis suggests its roles in primary and secondary metabolism in Saccharopolyspora erythraea. Appl Microbiol Biotechnol, 99(3):1399-413(2015) [pubmed] |
| 10.1007/s00253-014-6144-2; |
Keyword List
| curator keyword: Biological |
| submitter keyword: LC-MSMS,Saccharopolyspora erythraea, Acetylome |
Contact List
| Bang-Ce Ye |
|---|
| contact affiliation | Lab of Biosystems and Microanalysis, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, China. |
| contact email | bcye@ecust.edu.cn |
| lab head | |
| huang dan |
|---|
| contact affiliation | China |
| contact email | huangdan1003@163.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/11/PXD001238 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD001238
- Label: PRIDE project
- Name: Saccharopolyspora erythraea LC-MSMS
