PXD001118-1

PXD001118 is an original dataset announced via ProteomeXchange.

Title	Histione HCD and CID datasets for evaluation of search engines
Description	To identify confident spectra from histone peptides containing PTMs, we present a method in which one kind of modification is searched each time. We then combine the identifications of multiple search engines to obtain confident results. We find that two search engines, pFind and Mascot, identify most of the confident results. This study will be beneficial those who are interested in histone proteomics analysis.
HostingRepository	PRIDE
AnnounceDate	2014-09-01
AnnouncementXML	Submission_2014-09-01_01:02:20.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD001118
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Zuo-Fei Yuan
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	butanoylated residue; N6: N6; acetylated residue; phosphorylated residue; propanoylated residue; dimethylated residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2014-07-09 02:18:24	ID requested
⏵ 1	2014-09-01 01:02:21	announced
2	2014-10-23 05:00:04	announced	Updated project metadata.

Yuan ZF, Lin S, Molden RC, Garcia BA, Evaluation of proteomic search engines for the analysis of histone modifications. J Proteome Res, 13(10):4470-8(2014) [pubmed]

curator keyword: Biomedical

submitter keyword: histone, proteomics, post-translational modification, data analysis, search engine

Benjamin A. Garcia
contact affiliation	Epigenetics Program, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania
contact email	bgarci@mail.med.upenn.edu
lab head
Zuo-Fei Yuan
contact affiliation	UPenn
contact email	zuoyuan@mail.med.upenn.edu
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD001118
     1. Label: PRIDE project
     2. Name: Histione HCD and CID datasets for evaluation of search engines