PXD000997-1

PXD000997 is an original dataset announced via ProteomeXchange.

Title	Comprehensive Identification of Phosphorylation Sites on the Numb Endocytic Adaptor Protein
Description	Numb is an endocytic adaptor protein that functions in the endocytosis and intracellular trafficking of membrane receptors and adhesion molecules. Numb localization and function have been shown to be regulated by phosphorylation through atypcial protein kinase C at several key sites. Here, we use Liquid Chromatogrpahy, Tandem Mass Spectrometry to identify additional Numb phosphorylation sites not yet characterized.
HostingRepository	PRIDE
AnnounceDate	2014-12-16
AnnouncementXML	Submission_2014-12-16_09:06:14.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD000997
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Jonathan Krieger
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Oxidation; Phospho; Carbamidomethyl; Deamidated
Instrument	LTQ Orbitrap; LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2014-05-23 01:12:52	ID requested
⏵ 1	2014-12-16 09:06:16	announced

Krieger JR, Taylor P, Moran MF, McGlade CJ, Comprehensive identification of phosphorylation sites on the Numb endocytic adaptor protein. Proteomics, 15(2-3):434-46(2015) [pubmed]

curator keyword: Biomedical

submitter keyword: Numb

Phosphorylation

Cyclin D Kinase 5

Mass Spectrometry

Jane McGlade
contact affiliation	Hospital For Sick Children
contact email	jmcglade@sickkids.ca
lab head
Jonathan Krieger
contact affiliation	SickKids/University of Toronto
contact email	Jonathan.krieger@sickkids.ca
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2014/12/PXD000997

PRIDE project URI

• PRIDE
  1. PXD000997
     1. Label: PRIDE project
     2. Name: Comprehensive Identification of Phosphorylation Sites on the Numb Endocytic Adaptor Protein