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PXD049100

PXD049100 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Identification of binding proteins for PARP1 by TurboID
Description	To identify novel interaction partners of PARP1, we engineered a fusion of the full-length PARP1 with the TurboID enzyme and two negative controls. The first control omitted the bait protein PARP1, excluding the potential interaction of the TurboID protein itself. However, it bears the drawback of potentially obscuring real interactions due to the high flexibility and activity of free TurboID. The second control omitted exogenous biotin, serving as a complementary measure to address this concern.
HostingRepository	iProX
AnnounceDate	2024-02-01
AnnouncementXML	Submission_2024-02-01_21:15:39.162.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Mei Huang
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2024-02-01 21:15:18	ID requested
⏵ 1	2024-02-01 21:15:39	announced

Publication List

Dataset with its publication pending

Keyword List

submitter keyword: PARP1, TurboID

Contact List

Gaofeng Fan
contact affiliation	ShanghaiTech University
contact email	fangf@shanghaitech.edu.cn
lab head
Mei Huang
contact affiliation	ShanghaiTech University
contact email	huangmei@shanghaitech.edu.cn
dataset submitter

Full Dataset Link List

iProX dataset URI