PXD048151

PXD048151 is an original dataset announced via ProteomeXchange.

Title	EIF3H-interactome in Colorectal Cancer cell line (HCT116)
Description	To elucidate the molecular mechanism and search for EIF3H substrate(s) of EIF3H-mediated CRC progression, we performed immune-affinity purification and resolved the binding partners utilizing mass spectrometry. HCT116 cells transfected with empty vector or Flag-tagged EIF3H and then immunoprecipitated using anti-Flag M2 beads.The purified EIF3H protein complex was subjected to mass spectrometry analysis.
HostingRepository	iProX
AnnounceDate	2023-12-26
AnnouncementXML	Submission_2024-03-26_00:01:19.239.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Huilin Jin
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2023-12-27 18:04:45	ID requested
1	2023-12-27 18:05:14	announced
⏵ 2	2024-03-26 00:01:20	announced	2024-03-26: Update information.

Jin H, Huang X, Pan Q, Ma N, Xie X, Wei Y, Yu F, Wen W, Zhang B, Zhang P, Chen X, Wang J, Liu RY, Lin J, Meng X, Lee MH, The EIF3H-HAX1 axis increases RAF-MEK-ERK signaling activity to promote colorectal cancer progression. Nat Commun, 15(1):2551(2024) [pubmed]

submitter keyword: EIF3H-interactome, Colorectal Cancer cell line, HCT116

Monghong Lee
contact affiliation	The Sixth Affiliated Hospital, Sun Yat-sen University
contact email	limh33@mail.sysu.edu.cn
lab head
Huilin Jin
contact affiliation	The Sixth Affiliated Hospital, Sun Yat-sen University
contact email	jinhlin3@mail.sysu.edu.cn
dataset submitter

iProX dataset URI