PXD047248

PXD047248 is an original dataset announced via ProteomeXchange.

Title	The sequence of Fully Synthetic peptides, Phosphorylated Tau181, Tau217, and Tau231 Calibrators, have been confirmed by MALDI-ISD analysis
Description	We designed novel calibrators that include three phosphorylated Tau sites: Tau (1-22)-pT231, Tau (1-22)-pT217, and Tau (1-22)-pT181, respectively. Our synthesized peptides have various advantages compared with GSK3β-phosphorylated Tau-441. The novel fully synthesized calibrators not only improved the precision and stability of immunoassays but also served as potential calibrators for the diagnosis of AD.
HostingRepository	iProX
AnnounceDate	2023-11-24
AnnouncementXML	Submission_2024-03-06_00:11:45.799.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zhicheng Chen
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	ultraflex TOF/TOF

Revision	Datetime	Status	ChangeLog Entry
0	2023-11-26 18:56:00	ID requested
1	2024-02-29 17:47:05	announced
⏵ 2	2024-03-06 00:11:46	announced	2024-03-06: Update information.

Li X, Zeng H, Durairaj P, Wen W, Li T, Zhao Y, Liu Y, Liu X, Zhan L, Rao L, Yuan W, Guo T, Shen W, Cai H, Chen Z, Fully synthetic phosphorylated Tau181, Tau217, and Tau231 calibrators for Alzheimer's disease diagnosis. Front Aging Neurosci, 15():1340706(2023) [pubmed]

submitter keyword: Alzheimer's disease (AD), Tau, calibrator, diagnosis, immunoassay

Zhicheng Chen
contact affiliation	Center for Translational Research, Shenzhen Bay Laboratory
contact email	chenzc@szbl.ac.cn
lab head
Zhicheng Chen
contact affiliation	Center for Translational Research, Shenzhen Bay Laboratory
contact email	chenzc@szbl.ac.cn
dataset submitter

iProX dataset URI