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PXD046408-1

PXD046408 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMulti-omic Analyses Identified a Novel Biomarker in Abnormal Uterine Bleeding with Ovulatory Dysfunction
DescriptionThis study used multi-omic analyses to reveal the mechanisms underlying the progression of abnormal uterine bleeding with ovulatory dysfunction (AUB-O) to AUB with atypical hyperplasia/malignancy (AUB-M), discovering that SFRP4 influences human endometrial epithelial cells (hEECs) apoptosis, migration, invasion, proliferation, and colony formation via the Wnt pathway.
HostingRepositoryiProX
AnnounceDate2023-10-26
AnnouncementXMLSubmission_2023-10-26_00:11:31.842.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYunxiu Zhao
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-10-26 00:08:25ID requested
12023-10-26 00:11:32announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: multi-omic analyses, abnormal uterine bleeding with ovulatory dysfunction (AUB-O), abnormal uterine bleeding with atypical hyperplasia/malignancy (AUB-M), secreted frizzled-related protein 4 (SFRP4), Wnt pathway
Contact List
Jianhong Zhou
contact affiliationDepartment of Gynecology, Women's Hospital, Zhejiang University School of Medicine
contact emailzhoujh1117@zju.edu.cn
lab head
Yunxiu Zhao
contact affiliationDepartment of Gynecology, Women's Hospital, Zhejiang University School of Medicine
contact email12118532@zju.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI