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PXD045423-1

PXD045423 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleDynamics of single-cell protein covariation during epithelial-mesenchymal transition
DescriptionSingle cell proteomic dataset (~420 cells passing filter, 1827 proteins at 1% FDR and 4096 proteins post update via DART-ID) characterizing the Epithelial to Mesenchymal transition induced by TGF-B in MCF10A cells. Cells were sampled from day 0 (epithelial), day 3 (intermediate) and day 9 (sustained) treatment. The single cell samples were prepped using nPoP and prepared in the SCoPE2 format. Dataset also includes two bulk biological replicates (samples from day 0, 3 and 9 respectively) that were analyzed via label free DIA.
HostingRepositoryMassIVE
AnnounceDate2023-12-21
AnnouncementXMLSubmission_2023-12-21_16:14:05.278.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSaad Khan
SpeciesList scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationListacetylated residue; L-methionine sulfoxide
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-09-15 14:59:06ID requested
12023-12-21 16:14:05announced
Publication List
no publication
Keyword List
submitter keyword: Single Cell Proteomics, nPoP, SCoPE2, Bulk LF DIA, Epithelial to Mesenchymal Transition
Contact List
Nikolai Slavov
contact affiliationNortheastern University
contact emailnslavov@northeastern.edu
lab head
Saad Khan
contact affiliationNortheastern University
contact emailkhan.saad@northeastern.edu
dataset submitter
Full Dataset Link List
MassIVE dataset URI
Dataset FTP location
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