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PXD045231

PXD045231 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleRNF114 Co-IP experiments to identify binding partners
DescriptionTo identify the substrates of RNF114 in the context of PARylation-mediated DDR, we performed an IP-MS (immunoprecipitation coupled with MS) experiment, using cells treated with either H2O2 or H2O2+Talazoparib. We identified a large number of PARP1 peptides from the RNF114 immunoprecipitants only in H2O2-treated cells.
HostingRepositoryPRIDE
AnnounceDate2024-01-26
AnnouncementXMLSubmission_2024-01-26_06:30:03.874.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterChiho Kim
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-09-08 12:51:01ID requested
12024-01-26 06:30:04announced
Publication List
10.1126/sciadv.adg7752;
Li P, Zhen Y, Kim C, Liu Z, Hao J, Deng H, Deng H, Zhou M, Wang XD, Qin T, Yu Y, -mutated cancer. Sci Adv, 9(43):eadg7752(2023) [pubmed]
Keyword List
ProteomeXchange project tag: Cancer (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: RNF114 chromatin PARP1
Contact List
Yonghao Yu
contact affiliationDepartment of Molecular Pharmacology and Therapeutics Columbia University Irving Medical Center
contact emailyy3213@cumc.columbia.edu
lab head
Chiho Kim
contact affiliationColumbia university
contact emails164301@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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