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PXD044950-1

PXD044950 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleStructural basis for the toxicity of Legionella pneumophila effector SidH
DescriptionLegionella pneumophila (LP) secretes more than 300 effectors into the host cytosol to facilitate intracellular replication. One of these effectors, SidH does not have sequence similarityto proteins of known function and is toxic when overexpressed in host cells. In order to understand the mechanism and function, it is important to know what host factors, SidH interacts with in human cells. Using quantitative proteomics, we uncovered multiple host proteins as potential targets of SidH.
HostingRepositoryPRIDE
AnnounceDate2023-10-02
AnnouncementXMLSubmission_2023-10-02_06:39:25.031.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterrahulsharma
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02023-08-30 01:10:59ID requested
12023-10-02 06:39:25announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: SidH, LC-MS, interactors,Legionella pneumophila
Contact List
SagarBhogaraju
contact affiliationEMBL Grenoble
contact emailbhogaraju@embl.fr
lab head
rahulsharma
contact affiliationpost-doc
contact emailrsharma@embl.fr
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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