PXD044578-1
PXD044578 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Suppression and counter-suppression of plant immunity by an exo-1,3-glucanase of GH17 family and an elongation factor 1 of the rice blast fungus |
| Description | Fungal cell walls undergo continual remodeling during hyphal growth, development, infection and adaptation to environmental stress. Cell wall remodeling generates 1,3-glucan fragments by diverse endo-glycosyl hydrolases (GH), which are well-known pathogen-associated molecular patterns (PAMPs). How fungal pathogens evade plant immunity triggered by1,3-glucan fragments and associated GH proteins is not known. Here, we report a novel mechanism of immune evasion underlying the suppression of 1,3-glucan-triggered plant immunity by the blast fungus Magnaporthe oryzae. An exo-1,3-glucanase of the GH17 family, named Ebg1, is important for fungal cell wall integrity and virulence of M. oryzae. Ebg1 can hydrolyze 1,3-glucan and laminarin into glucose to prevent 1,3-glucan-triggered plant immunity, but also acts as a PAMP, independent of its hydrolase activity. Surprisingly, M. oryzae engages an elongation factor 1 alpha protein (EF1 to interact and co-localize with Ebg1 in the apoplast to suppress Ebg1-triggered immunity. Since both Ebg1 and EF1 are widely distributed in fungi, their interaction may be a conserved mechanism whereby fungal pathogens evade plant immunity and safeguard cell wall remodeling during infection. |
| HostingRepository | iProX |
| AnnounceDate | 2023-08-14 |
| AnnouncementXML | Submission_2023-08-14_19:30:24.862.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Ning Liu |
| SpeciesList | scientific name: Magnaporthe; NCBI TaxID: 148303; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2023-08-14 19:29:45 | ID requested | |
| ⏵ 1 | 2023-08-14 19:30:25 | announced | |
| 2 | 2024-02-21 18:43:23 | announced | 2024-02-22: Update Information |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: magnaporthe, barley, apoplastic fluid |
Contact List
| Xunli Lu | |
|---|---|
| contact affiliation | China Agricultural University |
| contact email | luxunli@cau.edu.cn |
| lab head | |
| Ning Liu | |
| contact affiliation | China Agricultural University |
| contact email | liuning@cau.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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