PXD042264 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Phosphoproteomic studies to identify targets and substrates of Protein kinase PfPK2 in human malaria parasite Plasmodium falciparum |
Description | The purpose of this project was to identify targets and substrates of Protein kinase PfPK2 in malaria parasite P. falciparum. These studies will help understand the mechanisms via which PfPK2, which is indispensable for the parasite survival, regulates parasite development. For this purpose, PfPK2-loxP parasite line was generated for conditional knock down of PfPK2 using rapamycin (RAP), which was used to induce the dimerization of active Cre-recombinase resulting in the depletion of PfPK2. |
HostingRepository | PRIDE |
AnnounceDate | 2023-10-18 |
AnnouncementXML | Submission_2023-10-18_04:05:56.083.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | KeshavaPrasad T. S. |
SpeciesList | scientific name: Plasmodium falciparum (isolate 3D7); NCBI TaxID: 36329; |
ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2023-05-16 08:32:35 | ID requested | |
⏵ 1 | 2023-10-18 04:05:56 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Phosphoproteomics,lasmodium falciparum, TMT, invasion, Orbitrap Fusion |
Contact List
T. S. Keshava Prasad,Ph.D. |
contact affiliation | Center for Systems Biology and Molecular Medicine Yenepoya Research Centre Yenepoya (Deemed to be University) University Road, Deralakatte Mangalore 575018, India |
contact email | tskprasad@gmail.com |
lab head | |
KeshavaPrasad T. S. |
contact affiliation | Institute of Bioinformatics, Bangalore, Karnataka, India. |
contact email | keshav@ibioinformatics.org |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD042264 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD042264
- Label: PRIDE project
- Name: Phosphoproteomic studies to identify targets and substrates of Protein kinase PfPK2 in human malaria parasite Plasmodium falciparum