PXD042264

PXD042264 is an original dataset announced via ProteomeXchange.

Title	Phosphoproteomic studies to identify targets and substrates of Protein kinase PfPK2 in human malaria parasite Plasmodium falciparum
Description	The purpose of this project was to identify targets and substrates of Protein kinase PfPK2 in malaria parasite P. falciparum. These studies will help understand the mechanisms via which PfPK2, which is indispensable for the parasite survival, regulates parasite development. For this purpose, PfPK2-loxP parasite line was generated for conditional knock down of PfPK2 using rapamycin (RAP), which was used to induce the dimerization of active Cre-recombinase resulting in the depletion of PfPK2.
HostingRepository	PRIDE
AnnounceDate	2023-10-18
AnnouncementXML	Submission_2023-10-18_04:05:56.083.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	KeshavaPrasad T. S.
SpeciesList	scientific name: Plasmodium falciparum (isolate 3D7); NCBI TaxID: 36329;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2023-05-16 08:32:35	ID requested
⏵ 1	2023-10-18 04:05:56	announced

Dataset with its publication pending

submitter keyword: Phosphoproteomics,lasmodium falciparum, TMT, invasion, Orbitrap Fusion

T. S. Keshava Prasad,Ph.D.
contact affiliation	Center for Systems Biology and Molecular Medicine Yenepoya Research Centre Yenepoya (Deemed to be University) University Road, Deralakatte Mangalore 575018, India
contact email	tskprasad@gmail.com
lab head
KeshavaPrasad T. S.
contact affiliation	Institute of Bioinformatics, Bangalore, Karnataka, India.
contact email	keshav@ibioinformatics.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD042264

PRIDE project URI

• PRIDE
  1. PXD042264
     1. Label: PRIDE project
     2. Name: Phosphoproteomic studies to identify targets and substrates of Protein kinase PfPK2 in human malaria parasite Plasmodium falciparum