PXD039365-2

PXD039365 is an original dataset announced via ProteomeXchange.

Title	Chromatin-associated OGT promotes hepatocellular carcinoma malignancy via activating ZNF263
Description	OGT, the only facilitator which attaches the monosaccharide to many oncogenic factors or tumor suppressors, has been suggested to play an influential role in tumorigenesis and metastasis of HCC. OGT interactome analyses indicates that disordered OGT may serve as a hub protein to activate the building of aberrant transcriptional regulatory complexes, supporting that this unique enzyme is an essential regulator in tumor progression. However, the function and related mechanisms by which OGT triggers HCC malignancy are still largely unknown
HostingRepository	iProX
AnnounceDate	2023-01-12
AnnouncementXML	Submission_2024-02-03_20:38:29.640.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yubo Liu
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2023-01-11 20:37:41	ID requested
1	2023-01-11 20:37:53	announced
⏵ 2	2024-02-03 20:38:30	announced	2024-02-04: Update publication information.

Wang L, Li G, Zhou Z, Ge C, Chen Q, Liu Y, Zhang N, Zhang K, Niu M, Li W, Zhong X, Wu S, Zhang J, Liu Y, Chromatin-associated OGT promotes the malignant progression of hepatocellular carcinoma by activating ZNF263. Oncogene, 42(30):2329-2346(2023) [pubmed]

submitter keyword: O-GlcNAc,ZNF263,OGT,Proteomics

Yubo Liu
contact affiliation	Dalian University of Technology
contact email	liuyubo@dlut.edu.cn
lab head
Yubo Liu
contact affiliation	Dalian University of Technology
contact email	liuyubo623@163.com
dataset submitter

iProX dataset URI