PXD039365
PXD039365 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Chromatin-associated OGT promotes hepatocellular carcinoma malignancy via activating ZNF263 |
Description | OGT, the only facilitator which attaches the monosaccharide to many oncogenic factors or tumor suppressors, has been suggested to play an influential role in tumorigenesis and metastasis of HCC. OGT interactome analyses indicates that disordered OGT may serve as a hub protein to activate the building of aberrant transcriptional regulatory complexes, supporting that this unique enzyme is an essential regulator in tumor progression. However, the function and related mechanisms by which OGT triggers HCC malignancy are still largely unknown |
HostingRepository | iProX |
AnnounceDate | 2023-01-12 |
AnnouncementXML | Submission_2024-02-03_20:38:29.640.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yubo Liu |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2023-01-11 20:37:41 | ID requested | |
1 | 2023-01-11 20:37:53 | announced | |
⏵ 2 | 2024-02-03 20:38:30 | announced | 2024-02-04: Update publication information. |
Publication List
Wang L, Li G, Zhou Z, Ge C, Chen Q, Liu Y, Zhang N, Zhang K, Niu M, Li W, Zhong X, Wu S, Zhang J, Liu Y, Chromatin-associated OGT promotes the malignant progression of hepatocellular carcinoma by activating ZNF263. Oncogene, 42(30):2329-2346(2023) [pubmed] |
Keyword List
submitter keyword: O-GlcNAc,ZNF263,OGT,Proteomics |
Contact List
Yubo Liu | |
---|---|
contact affiliation | Dalian University of Technology |
contact email | liuyubo@dlut.edu.cn |
lab head | |
Yubo Liu | |
contact affiliation | Dalian University of Technology |
contact email | liuyubo623@163.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |