PXD039325-1

PXD039325 is an original dataset announced via ProteomeXchange.

Title	Scentmarking communication in the female rat_C4PR_LIV
Description	Chemical communication in mammals is in part mediated through the deposition of scent marks in the environment. Volatile and non-volatile moleculesin the scent marksconvey important information about the donor animal, such as sex, social and reproductive status,and stimulatea response in the receptor animal. In rodents, most of the work about deciphering the molecular composition of scent markshas been focused on mice. In rats, by contrast, knowledge is limitedand the molecular complexity of scent marks is not as well described as in mice. In particular, the sources and roles of proteins in scent marks are largely undefined, with even less knowledge when we consider female rats. We therefore conducted a global proteomic analysis of scent marks from femalerats (Rattus norvegicus)to define the protein composition and then we investigated the role of scent marks in sexual communication. Our study revealed that protein pattern inscent marks greatly differsfrom that in naturally voided urine, indicatinga different tissue of41origin. In particular, female scent marks are dominated by lipocalins, notablymajor urinary proteins, whereas urinary output of these proteins is almost imperceptible.Further analysis revealed that the most plausible source of the components in scent marks are the clitoral glands,implying a critical role of theseaccessory glands in sexual communication in the rat.
HostingRepository	PRIDE
AnnounceDate	2023-05-29
AnnouncementXML	Submission_2023-05-29_08:44:38.159.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD039325
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	GuadalupeGomez-Baena
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF; Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2023-01-09 02:27:24	ID requested
⏵ 1	2023-05-29 08:44:38	announced

10.6019/PXD039325;

submitter keyword: Scents, MUPs, Norway rat

Robert J.Beynon
contact affiliation	Centre for Proteome Research, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, L69 7ZB, UK
contact email	rbeynon@liverpool.ac.uk
lab head
GuadalupeGomez-Baena
contact affiliation	Universidad de Cordoba
contact email	v52gobag@uco.es
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD039325
     1. Label: PRIDE project
     2. Name: Scentmarking communication in the female rat_C4PR_LIV