PXD039019-2
PXD039019 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | FOXA1 O-GlcNAcylation-mediated transcriptional switch governs metastasis capacity in breast cancer |
Description | The forkhead protein FOXA1 has been found to play a critical role in orchestrating hormonal-signaling network and to function as a pioneer factor to regulate breast-specific gene expression,However, whether interplay between O-GlcNAcylation and FOXA1 affects the genome-wide transcriptional activity of this TF and subsequently orchestrates downstream gene expression networks in breast cancer progression needs further elucidation. |
HostingRepository | iProX |
AnnounceDate | 2022-12-21 |
AnnouncementXML | Submission_2023-08-29_21:50:27.902.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yubo Liu |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; |
ModificationList | O-(N-acetylglucosamine-1-phosphoryl)-L-serine |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2022-12-21 00:56:41 | ID requested | |
1 | 2022-12-21 00:56:52 | announced | |
⏵ 2 | 2023-08-29 21:50:28 | announced | 2023-08-30: Update publication information. |
Publication List
Liu Y, Yu K, Kong X, Zhang K, Wang L, Zhang N, Chen Q, Niu M, Li W, Zhong X, Wu S, Zhang J, Liu Y, FOXA1 O-GlcNAcylation-mediated transcriptional switch governs metastasis capacity in breast cancer. Sci Adv, 9(33):eadg7112(2023) [pubmed] |
Keyword List
submitter keyword: O-GlcNAc, FOXA1, Proteomics |
Contact List
Yubo Liu | |
---|---|
contact affiliation | Dalian University of Technology |
contact email | liuyubo623@163.com |
lab head | |
Yubo Liu | |
contact affiliation | Dalian University of Technology |
contact email | liuyubo623@163.com |
dataset submitter |
Full Dataset Link List
iProX dataset URI |