PXD039019

PXD039019 is an original dataset announced via ProteomeXchange.

Title	FOXA1 O-GlcNAcylation-mediated transcriptional switch governs metastasis capacity in breast cancer
Description	The forkhead protein FOXA1 has been found to play a critical role in orchestrating hormonal-signaling network and to function as a pioneer factor to regulate breast-specific gene expression,However, whether interplay between O-GlcNAcylation and FOXA1 affects the genome-wide transcriptional activity of this TF and subsequently orchestrates downstream gene expression networks in breast cancer progression needs further elucidation.
HostingRepository	iProX
AnnounceDate	2022-12-21
AnnouncementXML	Submission_2023-08-29_21:50:27.902.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yubo Liu
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	O-(N-acetylglucosamine-1-phosphoryl)-L-serine
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2022-12-21 00:56:41	ID requested
1	2022-12-21 00:56:52	announced
⏵ 2	2023-08-29 21:50:28	announced	2023-08-30: Update publication information.

Liu Y, Yu K, Kong X, Zhang K, Wang L, Zhang N, Chen Q, Niu M, Li W, Zhong X, Wu S, Zhang J, Liu Y, FOXA1 O-GlcNAcylation-mediated transcriptional switch governs metastasis capacity in breast cancer. Sci Adv, 9(33):eadg7112(2023) [pubmed]

submitter keyword: O-GlcNAc, FOXA1, Proteomics

Yubo Liu
contact affiliation	Dalian University of Technology
contact email	liuyubo623@163.com
lab head
Yubo Liu
contact affiliation	Dalian University of Technology
contact email	liuyubo623@163.com
dataset submitter

iProX dataset URI