PXD038780-2

PXD038780 is an original dataset announced via ProteomeXchange.

Title	Proteomes of Micro- and Nano-Sized Carriers Engineered from Red Blood Cells
Description	Erythrocyte-derived systems offer a potential platform for delivering biomedical cargos. Although the importance of specific proteins associated with biodistribution and pharmacokinetics of these particles has been recognized, it remains to be explored whether some of the key transmembrane and cytoskeletal proteins, responsible for immune-modulatory effects and mechanical integrity of the particles, are retained. Herein, the main objective of our project is to examine the proteomes of micro- and nano-sized erythrocyte ghosts doped with near-infrared agent, indocyanine green, and compare them with those of native red blood cells (RBCs). Our findings highlight the importance of engineering methods in fabricating erythrocyte-based systems with appropriate proteomics for ultimate clinical applications.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:12:34.619.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Chi Hua Lee
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2022-12-12 22:56:06	ID requested
1	2023-02-17 03:25:16	announced
⏵ 2	2023-11-14 08:12:37	announced	2023-11-14: Updated project metadata.

Lee CH, Tang JC, Hendricks NG, Anvari B, Proteomes of Micro- and Nanosized Carriers Engineered from Red Blood Cells. J Proteome Res, 22(3):896-907(2023) [pubmed]

submitter keyword: tandem mass spectrometry,bioinformatics, erythrocyte, drug delivery

Bahman Anvari
contact affiliation	Bioengineering department, University of Californai, Riverside
contact email	anvarib@ucr.edu
lab head
Chi Hua Lee
contact affiliation	UC Riverside
contact email	clee188@ucr.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/02/PXD038780

PRIDE project URI

• PRIDE
  1. PXD038780
     1. Label: PRIDE project
     2. Name: Proteomes of Micro- and Nano-Sized Carriers Engineered from Red Blood Cells