PXD037648-1
PXD037648 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation |
Description | SENP1 deSUMOylates RIPK1 in TNF-R1 signaling complex (TNF-RSC), keeping RIPK1 in check. Loss of SENP1 leads to SUMOylation of RIPK1, which re-orchestrates TNF-RSC and modulates the ubiquitination patterns and activity of RIPK1. |
HostingRepository | iProX |
AnnounceDate | 2022-10-24 |
AnnouncementXML | Submission_2022-10-24_00:34:56.150.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Bing Shan |
SpeciesList | scientific name: Mus musculus; NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF-X |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2022-10-24 00:34:37 | ID requested | |
⏵ 1 | 2022-10-24 00:34:56 | announced | |
2 | 2022-12-07 23:16:18 | announced | 2022-12-08: Update publication information. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: SENP1 |
Contact List
Daichao Xu | |
---|---|
contact affiliation | Shanghai institute of Organic Chemistry,CAS |
contact email | xudaichao@sioc.ac.cn |
lab head | |
Bing Shan | |
contact affiliation | Shanghai institute of Organic Chemistry,CAS |
contact email | shanbing@sioc.ac.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |