PXD037648

PXD037648 is an original dataset announced via ProteomeXchange.

Title	SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation
Description	SENP1 deSUMOylates RIPK1 in TNF-R1 signaling complex (TNF-RSC), keeping RIPK1 in check. Loss of SENP1 leads to SUMOylation of RIPK1, which re-orchestrates TNF-RSC and modulates the ubiquitination patterns and activity of RIPK1.
HostingRepository	iProX
AnnounceDate	2022-10-24
AnnouncementXML	Submission_2022-12-07_23:16:16.492.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Bing Shan
SpeciesList	scientific name: Mus musculus; NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2022-10-24 00:34:37	ID requested
1	2022-10-24 00:34:56	announced
⏵ 2	2022-12-07 23:16:18	announced	2022-12-08: Update publication information.

Yan L, Zhang T, Wang K, Chen Z, Yang Y, Shan B, Sun Q, Zhang M, Zhang Y, Zhong Y, Liu N, Gu J, Xu D, SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation. Nat Commun, 13(1):7153(2022) [pubmed]

submitter keyword: SENP1

Daichao Xu
contact affiliation	Shanghai institute of Organic Chemistry,CAS
contact email	xudaichao@sioc.ac.cn
lab head
Bing Shan
contact affiliation	Shanghai institute of Organic Chemistry,CAS
contact email	shanbing@sioc.ac.cn
dataset submitter

iProX dataset URI