PXD037587

PXD037587 is an original dataset announced via ProteomeXchange.

Title	T cells of colorectal cancer patients’ stimulated by neoantigenic and cryptic peptides better recognize autologous tumor cells
Description	Immunopeptidome analysis of patient-derived colorectal cancer cell lines HROC113 and HROC285 T0 M2 from the HROC collection [Mullins et al. Cancers (Basel). 2019;11(10):1520. doi: 10.3390/cancers11101520] was performed to characterize the natural HLA class I presented ligandome in native as well as IFNγ treated cells.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:05:34.591.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Markus Löffler
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2022-10-20 02:08:15	ID requested
1	2023-03-10 16:21:04	announced
⏵ 2	2023-11-14 08:05:35	announced	2023-11-14: Updated project metadata.

Schwarz S, Schmitz J, L, ö, ffler MW, Ghosh M, Rammensee HG, Olshvang E, Markel M, Mockel-Tenbrinck N, Dzionek A, Krake S, Arslan B, Kampe KD, Wendt A, Bauer P, Mullins CS, Schlosser A, Linnebacher M, T cells of colorectal cancer patients' stimulated by neoantigenic and cryptic peptides better recognize autologous tumor cells. J Immunother Cancer, 10(12):(2022) [pubmed]

submitter keyword: HLA-presented peptides

neoepitope, Colorectal Cancer, Human, HLA class I, Antigen Presentation,LC-MSMS

Hans-Georg Rammensee
contact affiliation	Department of Immunology, Interfaculty Institute for Cell Biology, University of Tübingen, Tübingen, Germany
contact email	rammensee@uni-tuebingen.de
lab head
Markus Löffler
contact affiliation	University of Tübingen
contact email	markus.loeffler@med.uni-tuebingen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD037587

PRIDE project URI

• PRIDE
  1. PXD037587
     1. Label: PRIDE project
     2. Name: T cells of colorectal cancer patients’ stimulated by neoantigenic and cryptic peptides better recognize autologous tumor cells