PXD037584 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | GPI-glycan structures of human Prion (M232R) from knock-in mice_LC-MSMS |
Description | To determine glycosylphosphatidylinositol (GPI) structures of human prion proteins with M232R mutation isolated from knock-in mice those express human prion protein instead of mouse one. |
HostingRepository | PRIDE |
AnnounceDate | 2023-03-08 |
AnnouncementXML | Submission_2023-03-08_08:23:29.733.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD037584 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | TetsuyaHirata |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | acetylated residue; iodoacetamide derivatized residue |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-10-20 02:03:03 | ID requested | |
⏵ 1 | 2023-03-08 08:23:30 | announced | |
2 | 2023-11-14 07:56:35 | announced | 2023-11-14: Updated project metadata. |
Publication List
10.6019/PXD037584; |
Kobayashi A, Hirata T, Shimazaki T, Munesue Y, Aoshima K, Kimura T, Nio-Kobayashi J, Hasebe R, Takeuchi A, Matsuura Y, Kusumi S, Koga D, Iwasaki Y, Kinoshita T, Mohri S, Kitamoto T, A point mutation in GPI-attachment signal peptide accelerates the development of prion disease. Acta Neuropathol, 145(5):637-650(2023) [pubmed] |
Keyword List
submitter keyword: GPI, GPI side chain, Prion, Brain, knock-in mouse, Human |
Contact List
TarohKinoshita |
contact affiliation | Research Institute for Microbial Diseases, Osaka University |
contact email | tkinoshi@biken.osaka-u.ac.jp |
lab head | |
TetsuyaHirata |
contact affiliation | Department of Biochemistry, Duke University School of Medicine |
contact email | tetsuya.hirata@duke.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD037584 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD037584
- Label: PRIDE project
- Name: GPI-glycan structures of human Prion (M232R) from knock-in mice_LC-MSMS