PXD037584

PXD037584 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	GPI-glycan structures of human Prion (M232R) from knock-in mice_LC-MSMS
Description	To determine glycosylphosphatidylinositol (GPI) structures of human prion proteins with M232R mutation isolated from knock-in mice those express human prion protein instead of mouse one.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:56:33.235.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD037584
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Tetsuya Hirata
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-10-20 02:03:03	ID requested
1	2023-03-08 08:23:30	announced
⏵ 2	2023-11-14 07:56:35	announced	2023-11-14: Updated project metadata.

Publication List

10.6019/PXD037584;
Kobayashi A, Hirata T, Shimazaki T, Munesue Y, Aoshima K, Kimura T, Nio-Kobayashi J, Hasebe R, Takeuchi A, Matsuura Y, Kusumi S, Koga D, Iwasaki Y, Kinoshita T, Mohri S, Kitamoto T, A point mutation in GPI-attachment signal peptide accelerates the development of prion disease. Acta Neuropathol, 145(5):637-650(2023) [pubmed]

10.6019/PXD037584;

Kobayashi A, Hirata T, Shimazaki T, Munesue Y, Aoshima K, Kimura T, Nio-Kobayashi J, Hasebe R, Takeuchi A, Matsuura Y, Kusumi S, Koga D, Iwasaki Y, Kinoshita T, Mohri S, Kitamoto T, A point mutation in GPI-attachment signal peptide accelerates the development of prion disease. Acta Neuropathol, 145(5):637-650(2023) [pubmed]

Keyword List

submitter keyword: GPI, GPI side chain, Prion, Brain, knock-in mouse, Human

submitter keyword: GPI, GPI side chain, Prion, Brain, knock-in mouse, Human

Contact List

Taroh Kinoshita
contact affiliation	Research Institute for Microbial Diseases, Osaka University
contact email	tkinoshi@biken.osaka-u.ac.jp
lab head
Tetsuya Hirata
contact affiliation	Department of Biochemistry, Duke University School of Medicine
contact email	tetsuya.hirata@duke.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD037584
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/03/PXD037584

PRIDE project URI

Repository Record List

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