PXD036472 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic profiling of urinary small extracellular vesicles deciphers the molecular signature of children with viral pneumonia:a pilot study |
Description | There is evidence that small extracellular vesicles (sEV) play a vital role in immune responses to viral and bacterial infection. Characteristics of urinary sEV, however, from pediatric patients with pneumonia remain to be ill-defined. In this study, we isolated sEV from urines of children with viral pneumonia or Mycoplasma pneumoniae pneumonia and healthy children and performed label-free proteomic analysis of these vesicles and identified viral-specific differentially expressed proteins compared with healthy children. Results of functional enrichment analysis suggest that the proteomic profiles of urinary sEV serve as the basis for understanding the fundamental biology of infection in children with viral pneumonia. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:58:03.836.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Dongrui Ji |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-09-02 06:33:51 | ID requested | |
1 | 2023-01-12 19:33:39 | announced | |
⏵ 2 | 2023-11-14 08:58:04 | announced | 2023-11-14: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Pneumonia,Pediatrics,Infection,Extracellular vesicle,Proteomic, Immunology |
Contact List
Lin Yang |
contact affiliation | Department of Clinic Laboratory, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China |
contact email | lynyang73@163.com |
lab head | |
Dongrui Ji |
contact affiliation | Wayen Biotechnologies |
contact email | 878137865@qq.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD036472
- Label: PRIDE project
- Name: Proteomic profiling of urinary small extracellular vesicles deciphers the molecular signature of children with viral pneumonia:a pilot study