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PXD036268-2

PXD036268 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleOne-pot comparative analysis and characterization of MCF-7 and MCF-10A cell lines
DescriptionA comparison of different energetics based techniques for the characterization of two mammalian breast cell lines, MCF-7 a luminal A breast cancer cell line and MCF-10A a normal human breast cell line. The techniques of stability of proteins from rates of oxidation (SPROX), thermal proteome profiling (TPP), and conventional expression level analyses were compared and the relative advantages and disadvantages are discussed.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:58:32.994.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMorgan Bailey
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue; methylthiolated residue; monohydroxylated residue
InstrumentOrbitrap Exploris 480
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-08-25 13:15:32ID requested
12023-02-22 16:51:06announced
22023-11-14 08:58:33announced2023-11-14: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Thermodynamics, thermal denaturation, chemical denaturation, protein folding
Contact List
Michael C. Fitzgerald
contact affiliationPI of the Fitzgerald lab at Duke University Depratment of Chemistry
contact emailmichael.c.fitzgerald@duke.edu
lab head
Morgan Bailey
contact affiliationDuke University Department of Chemistry
contact emailmorgan.a.bailey@duke.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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