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PXD036161-1

PXD036161 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHigh-throughput proteomics of the 26 medically most important elapids and vipers from sub-Saharan Africa
DescriptionVenomous snakes are important parts of the ecosystem, and their behavior and evolution have been shaped by their surrounding environments over the eons. This is reflected in their venoms, which are typically highly adapted for their biological niche, including their diet and defense mechanisms for deterring predators. Sub-Saharan Africa is rich in venomous snake species, of which many are dangerous to humans due to the high toxicity of their venoms and their ability to effectively deliver large amounts of venom into their victims via their bite. In this study, the venoms of 26 of sub-Saharan Africa’s medically most relevant elapid and viper species were subjected to parallelized toxicovenomics analysis. The analysis included venom proteomics and enables a robust comparison of venom profiles between species. Moreover, two new venom proteomes (N. anchietae and E. leucogaster) are presented here for the first time.
HostingRepositoryPRIDE
AnnounceDate2022-10-17
AnnouncementXMLSubmission_2022-10-17_06:10:37.324.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterCarolO'Brien
SpeciesList scientific name: Cerastes cerastes; NCBI TaxID: 8697; scientific name: Hemachatus haemachatus; NCBI TaxID: 8626; scientific name: Dendroaspis viridis; NCBI TaxID: 8621; scientific name: Dendroaspis angusticeps (Eastern green mamba) (Naja angusticeps); NCBI TaxID: 8618; scientific name: Naja nivea; NCBI TaxID: 8655; scientific name: Dendroaspis polylepis; NCBI TaxID: 8624; scientific name: Naja katiensis; NCBI TaxID: 409859; scientific name: Naja haje; NCBI TaxID: 8639; scientific name: Echis pyramidum; NCBI TaxID: 8700; scientific name: Naja senegalensis; NCBI TaxID: 862238; scientific name: Naja nigricollis; NCBI TaxID: 8654; scientific name: Naja melanoleuca; NCBI TaxID: 8643; scientific name: Naja ashei; NCBI TaxID: 696811; scientific name: Naja annulifera; NCBI TaxID: 96794; scientific name: Bitis arietans; NCBI TaxID: 8692; scientific name: Bitis nasicornis; NCBI TaxID: 8695; scientific name: Naja anchietae; NCBI TaxID: 263737; scientific name: Naja pallida; NCBI TaxID: 8658; scientific name: Naja nigricincta; NCBI TaxID: 409860; scientific name: Bitis rhinoceros; NCBI TaxID: 715877; scientific name: Echis ocellatus; NCBI TaxID: 99586; scientific name: Bitis gabonica; NCBI TaxID: 8694; scientific name: Naja nubiae; NCBI TaxID: 186441; scientific name: Echis leucogaster; NCBI TaxID: 504457; scientific name: Naja mossambica; NCBI TaxID: 8644; scientific name: Dendroaspis jamesoni; NCBI TaxID: 8623;
ModificationListacetylated residue; monohydroxylated residue; deamidated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-08-19 00:35:27ID requested
12022-10-17 06:10:37announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: snakebite envenoming,snake venom, venomics
Contact List
Andreas H.Laustsen
contact affiliationTechnical University of Denmark
contact emailahola@bio.dtu.dk
lab head
CarolO'Brien
contact affiliationTechnical University of Denmark
contact emailcmaob@dtu.dk
dataset submitter
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