PXD035829-1
PXD035829 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Phosphoproteome and proteome of mouse hepatocyte maturation and human hepatic reprogramming |
Description | To identify central protein kinases that potentially promote the maturation, we chemically induced liver progenitor cells (CLiPs) from mouse hepatocytes using a previously established protocol, and profiled the phosphoproteome and proteome of freshly isolated primary mouse hepatocytes (MHs) and ALBUMIN+ hepatocytes (CLiP-Hep) cells. To systematically interrogate the early regulatory events of hepatic reprogramming, we profiled the Phosphoproteome and proteome in human dermal fibroblasts (HDFs) at 2.25 days (FHH-2.25d) and 5 days (FHH-5d) after infection of lenti-virus encoding three liver-specific transcription factors, FOXA3, HNF1A and HNF4A (FHH). In this analysis, HDF infected with lenti-virus expressing GFP for 2.25 days (GFP) were used as control. |
HostingRepository | iProX |
AnnounceDate | 2022-08-05 |
AnnouncementXML | Submission_2022-08-05_09:32:26.897.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yangyang Yuan |
SpeciesList | scientific name: Homo sapiens; NCBI TaxID: 9606; scientific name: Mus musculus; NCBI TaxID: 10090; |
ModificationList | phosphorylated residue |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2022-08-05 09:31:02 | ID requested | |
⏵ 1 | 2022-08-05 09:32:27 | announced | |
2 | 2023-03-01 22:59:27 | announced | 2023-03-02: Update publication information. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Phosphoproteome, proteome, hepatocyte maturation, hepatic reprogramming, TMT |
Contact List
Yu Xue | |
---|---|
contact affiliation | Huazhong University of Science and Technology, Wuhan, China |
contact email | xueyu@hust.edu.cn |
lab head | |
Yangyang Yuan | |
contact affiliation | ShanghaiTech University, Shanghai, China |
contact email | yuanyy@shanghaitech.edu.cn |
dataset submitter |
Full Dataset Link List
iProX dataset URI |