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PXD035662-1

PXD035662 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic analysis of MRSA252 secretome and membrane vesicles
DescriptionThe secretome of the Staphylococcus aureus includes specific pathway-exported proteins, as well as cytoplasmic proteins with unknown mechanisms of secretion. As one component of the S. aureus secretome, extracellular membrane vesicles (MVs) are also comprised of secreted and cytoplasmic proteins. However, the contribution of MVs to the secretome of S. aureus has not been investigated. To address this, we performed a proteomic analysis of MVs purified from S. aureus strain MRSA252 along with a similar analysis of the culture supernatans before (S+MV) and after (S-MV) depletion of MVs.
HostingRepositoryPRIDE
AnnounceDate2023-01-26
AnnouncementXMLSubmission_2023-01-26_01:41:07.451.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDivakara SSMUppu
SpeciesList scientific name: Staphylococcus aureus; NCBI TaxID: 1280;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-08-01 02:05:23ID requested
12023-01-26 01:41:07announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: MRSA252, membrane vesicles, Staphylococcus aureus, secretome, LC-MS/MS
Contact List
Jean ClaireLee
contact affiliationAssociate Professor, Harvard Medical School Lead Investigator, Brigham and Women's Hospital 181 Longwood Avenue, Boston, Massachusetts USA 02115
contact emailJCLEE@BWH.HARVARD.EDU
lab head
Divakara SSMUppu
contact affiliationBrigham and Women's Hospital and Harvard Medical School
contact emaildivakarauppu@gmail.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
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