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PXD035652

PXD035652 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic and phosphoproteomic profiling reveals the oncogenic role of protein kinase D family kinases in cholangiocarcinoma
DescriptionTo systematically characterize the kinome of the CCA, the proteomic and phosphoproteomic profiling of CCA tumors with NATs was performed using LC-MS/MS (Figure 1). After the extraction and digestion of proteins from each sample, peptides were labeled with TMT reagent and fractionated, and phosphopeptides were enriched with immobilized metal ion affinity chromatography (IMAC).
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_07:59:34.141.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitteryun lu
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListphosphorylated residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-08-01 01:56:19ID requested
12022-10-17 22:42:37announced
22023-11-14 07:59:36announced2023-11-14: Updated project metadata.
Publication List
Lu Y, Li X, Zhao K, Shi Y, Deng Z, Yao W, Wang J, Proteomic and Phosphoproteomic Profiling Reveals the Oncogenic Role of Protein Kinase D Family Kinases in Cholangiocarcinoma. Cells, 11(19):(2022) [pubmed]
Keyword List
ProteomeXchange project tag: Cancer (B/D-HPP), Biology/Disease-Driven Human Proteome Project (B/D-HPP), Human Proteome Project
submitter keyword: protein kinase, phosphoproteomics,cholangiocarcinoma, protein kinase D
Contact List
Biliary and Pancreatic Surgery/Cancer Research Center
contact affiliationTongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
contact emaildrlyly@163.com
lab head
yun lu
contact affiliationHuazhong University of Science and Technology
contact emaildrlyly@163.com
dataset submitter
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Dataset FTP location
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