PXD034335-1

PXD034335 is an original dataset announced via ProteomeXchange.

Title	Identification of ubiquitination targets of UHRF1
Description	The reversible attachment of ubiquitin governs the interaction, activity and degradation of proteins whereby the type and target of this conjugation determine the biological response. The investigation of this complex and multi-faceted protein ubiquitination mostly relies on painstaking biochemical analyses. Here, we employ recombinant binding domains to identify the UHRF1 dependent ubiquitinated proteins by liquid chromatography tandem mass spectrometry (LC-MS/MS).
HostingRepository	PRIDE
AnnounceDate	2023-01-30
AnnouncementXML	Submission_2023-01-30_01:40:45.665.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	IgnasiForne
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap

Revision	Datetime	Status	ChangeLog Entry
0	2022-06-06 01:13:41	ID requested
⏵ 1	2023-01-30 01:40:46	announced
2	2023-11-14 07:48:38	announced	2023-11-14: Updated project metadata.

Qin W, Steinek C, Kolobynina K, Forn, é I, Imhof A, Cardoso MC, Leonhardt H, Probing protein ubiquitination in live cells. Nucleic Acids Res, 50(21):e125(2022) [pubmed]

submitter keyword: Posttranslational modifications (PMT), ubiquitination, protein degradation, DNA methylation, Heterochromatin binding protein (HP1),UHFR1

Prof. Dr. HeinrichLeonhardt
contact affiliation	Faculty of Biology, Ludwig-Maximilians-Universität München, Großhaderner Str. 2, 82152 Planegg-Martinsried, Germany
contact email	h.leonhardt@lmu.de
lab head
IgnasiForne
contact affiliation	Biomedical Center-LMU
contact email	ignasi.forne@lrz.uni-muenchen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/01/PXD034335

PRIDE project URI

• PRIDE
  1. PXD034335
     1. Label: PRIDE project
     2. Name: Identification of ubiquitination targets of UHRF1