PXD033988

PXD033988 is an original dataset announced via ProteomeXchange.

Title	Proteomics study of antenatal hydronephrosis patients on amniotic fluid
Description	In this study, we carried out a comprehensive comparative proteomic and transcriptomic analysis of exosomes in amniotic fluid supernatant and cells in amniotic fluid precipitation of severe fetal hydronephrosis patients to identify candidate biomarkers with diagnostic potential. As the investigation of mechanisms underlying those predicted target genes remain scarce, our studies also provide valuable indications for further researches exploring the role of those genes in fundamental biology or diagnosis of nephrosis.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_09:06:15.767.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Lei Dai
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2022-05-19 03:24:11	ID requested
1	2023-10-24 07:07:23	announced
⏵ 2	2023-11-14 09:06:17	announced	2023-11-14: Updated project metadata.

Li J, Fu Y, Liu Q, Shen K, Yao R, Fu Y, Lu Y, Xie M, Jian W, Guo M, Dai L, Zhang W, Multiomics-based study of amniotic fluid small extracellular vesicles identified Moesin as a biomarker for antenatal hydronephrosis. Clin Transl Med, 13(8):e1360(2023) [pubmed]

submitter keyword: Human,antenatal hydronephrosis,LC-MSMS,amniotic fluid

Weishe Zhang
contact affiliation	Department of Obstetrics, Xiangya Hospital Central South University, Changsha, China
contact email	zhangweishe@yeah.net
lab head
Lei Dai
contact affiliation	Department of Obstetrics, Xiangya Hospital Central South University, Changsha
contact email	austindai@hotmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/10/PXD033988

PRIDE project URI

• PRIDE
  1. PXD033988
     1. Label: PRIDE project
     2. Name: Proteomics study of antenatal hydronephrosis patients on amniotic fluid