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PXD033723

PXD033723 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlediaPASEF analysis of exosomes from stem cells
Descriptionwe used highly sensitive mass spectrometry diaPASEF (parallel accumulation serial fragmentation combined with the data-independent acquisition)27 to quantify proteins of exosomes derived from umbilical cord mesenchymal stem cells (UCMSCs) and rat bone marrow stem cells (BMSCs). 4206 human proteins and 5341 rat proteins were detected from UCMSC exosomes and BMSC exosomes, respectively. From these proteins, we identified the core proteome of exosomes which is common to UCMSCs and BMSCs. In addition, we identified two exosomal proteins which can be used as the potential marker for differentiation ability of BMSCs. In summary, the exosomal quantitative proteome presented by this study can serve as a valuable resource for further fundamental and biomarker researches of exosomes.
HostingRepositoryiProX
AnnounceDate2022-05-05
AnnouncementXMLSubmission_2023-12-25_20:06:37.256.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterChuanqi Zhong
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606; scientific name: Rattus norvegicus; NCBI TaxID: 10116;
ModificationListNo PTMs are included in the dataset
InstrumenttimsTOF Pro
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-05-05 18:38:26ID requested
12022-05-05 18:38:37announced
22023-12-25 20:06:38announced2023-12-26: Update information.
Publication List
Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ, Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells. Proteomics, 23(1):e2200204(2023) [pubmed]
Keyword List
submitter keyword: Stem cells, diaPASEF
Contact List
Chuanqi Zhong
contact affiliationXiamen University
contact emailzhongcq@xmu.edu.cn
lab head
Chuanqi Zhong
contact affiliationXiamen University
contact emailzhongcq@xmu.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI