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PXD032234-2

PXD032234 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCellular and culture medium proteomes from umbilical cord mesenchymal stem cell and human umbilical vein endothelial cells
DescriptionApplication of umbilical cord mesenchymal stem cell-derived conditioned media (HUCMSC-CM) to treat severe, progressive PAH. Serial infusions of HUCMSC-CM resulted in marked clinical and hemodynamic improvement after 6 months, and showed no adverse events. Differential expression analysis between conditioned media and cells was used to identify molecular processes with a putative role in treatment benefit.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_07:35:32.610.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterMichael Mülleder
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumenttimsTOF Pro 2
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-03-11 10:49:51ID requested
12022-05-04 05:15:56announced
22023-11-14 07:35:33announced2023-11-14: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Human, PAH,HUCMSC, HUVEC
Contact List
Prof. Dr. Georg Hansmann
contact affiliationDepartment of Pediatric Cardiology and Critical Care; Pulmonary Vascular Research Center; Hannover Medical School; Hannover; Germany
contact emailhansmann.georg@mh-hannover.de
lab head
Michael Mülleder
contact affiliationCore Facility -High-Throughput Mass Spectrometry, Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health (BIH), Berlin, Germany
contact emailmichael.muelleder@charite.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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