PXD032139 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | N-terminal processing of beta and gamma actin in MEF cells |
Description | Actin is one of the most essential and abundant intracellular proteins, playing an essential physiological role as the major constituent of the actin cytoskeleton. Two cytoplasmic actins, beta- and gamma-actin, are encoded by different genes, but their amino acid sequences differ only by four conservative substitutions at the N-terminus, making it very difficult to dissect their individual regulation in vivo. The majority of actins are N-terminally acetylated, following the removal of N-terminal Met. Here, we analyzed beta and gamma cytoplasmic actin N-termini in different actin preparations. |
HostingRepository | PRIDE |
AnnounceDate | 2023-03-11 |
AnnouncementXML | Submission_2023-03-11_03:05:44.976.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD032139 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | DaweiDong |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-03-09 00:46:53 | ID requested | |
⏵ 1 | 2023-03-11 03:05:45 | announced | |
2 | 2023-11-14 08:41:16 | announced | 2023-11-14: Updated project metadata. |
Publication List
10.6019/PXD032139; |
Chen L, Vedula P, Tang HY, Dong DW, Kashina AS, Differential N-terminal processing of beta and gamma actin. iScience, 25(10):105186(2022) [pubmed] |
Keyword List
submitter keyword: mouse, MEF, actin |
Contact List
AnnaKashina |
contact affiliation | University of Pennsylvania |
contact email | akashina@upenn.edu |
lab head | |
DaweiDong |
contact affiliation | University of Pennsylvania |
contact email | dawei.w.dong@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD032139
- Label: PRIDE project
- Name: N-terminal processing of beta and gamma actin in MEF cells