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PXD032139

PXD032139 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleN-terminal processing of beta and gamma actin in MEF cells
DescriptionActin is one of the most essential and abundant intracellular proteins, playing an essential physiological role as the major constituent of the actin cytoskeleton. Two cytoplasmic actins, beta- and gamma-actin, are encoded by different genes, but their amino acid sequences differ only by four conservative substitutions at the N-terminus, making it very difficult to dissect their individual regulation in vivo. The majority of actins are N-terminally acetylated, following the removal of N-terminal Met. Here, we analyzed beta and gamma cytoplasmic actin N-termini in different actin preparations.
HostingRepositoryPRIDE
AnnounceDate2023-11-14
AnnouncementXMLSubmission_2023-11-14_08:41:15.597.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD032139
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterDawei Dong
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02022-03-09 00:46:53ID requested
12023-03-11 03:05:45announced
22023-11-14 08:41:16announced2023-11-14: Updated project metadata.
Publication List
10.6019/PXD032139;
Chen L, Vedula P, Tang HY, Dong DW, Kashina AS, Differential N-terminal processing of beta and gamma actin. iScience, 25(10):105186(2022) [pubmed]
Keyword List
submitter keyword: mouse, MEF, actin
Contact List
Anna Kashina
contact affiliationUniversity of Pennsylvania
contact emailakashina@upenn.edu
lab head
Dawei Dong
contact affiliationUniversity of Pennsylvania
contact emaildawei.w.dong@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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