PXD032100 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Cancer-derived branched-chain ketoacids modulate macrophage polarization and metabolic reprogramming |
Description | This study aims to uncover the effects of cancer-derived branched-chain ketoacids on macrophage polarization and the underlying mechanism. We uncovered the global responses of branched-chain ketoacids-stimulated macrophages by proteomics analysis. Functional enrihment analysis indicated that these ketoacids significantly altered macrophage metabolism, apoptosis and phagocytosis. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:55:53.528.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Zhengnan Cai |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2022-03-07 03:50:42 | ID requested | |
1 | 2022-10-04 00:49:12 | announced | |
⏵ 2 | 2023-11-14 08:55:54 | announced | 2023-11-14: Updated project metadata. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: macrophages, polarization,Branched-chain ketoacids |
Contact List
Wolfram Weckwerth |
contact affiliation | Head of Molecular Systems Biology Lab (MOSYS), Vice-Head Department Functional & Evolutionary Ecology, Head of Large Instrument Facility for Mass Spectrometry in Life Sciences, Chair of the Vienna Metabolomics Center (VIME) |
contact email | wolfram.weckwerth@univie.ac.at |
lab head | |
Zhengnan Cai |
contact affiliation | University of Vienna |
contact email | zhengnan.cai@univie.ac.at |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD032100 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD032100
- Label: PRIDE project
- Name: Cancer-derived branched-chain ketoacids modulate macrophage polarization and metabolic reprogramming