PXD032100

PXD032100 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Cancer-derived branched-chain ketoacids modulate macrophage polarization and metabolic reprogramming
Description	This study aims to uncover the effects of cancer-derived branched-chain ketoacids on macrophage polarization and the underlying mechanism. We uncovered the global responses of branched-chain ketoacids-stimulated macrophages by proteomics analysis. Functional enrihment analysis indicated that these ketoacids significantly altered macrophage metabolism, apoptosis and phagocytosis.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:55:53.528.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zhengnan Cai
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2022-03-07 03:50:42	ID requested
1	2022-10-04 00:49:12	announced
⏵ 2	2023-11-14 08:55:54	announced	2023-11-14: Updated project metadata.

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: macrophages, polarization,Branched-chain ketoacids

submitter keyword: macrophages, polarization,Branched-chain ketoacids

Contact List

Wolfram Weckwerth
contact affiliation	Head of Molecular Systems Biology Lab (MOSYS), Vice-Head Department Functional & Evolutionary Ecology, Head of Large Instrument Facility for Mass Spectrometry in Life Sciences, Chair of the Vienna Metabolomics Center (VIME)
contact email	wolfram.weckwerth@univie.ac.at
lab head
Zhengnan Cai
contact affiliation	University of Vienna
contact email	zhengnan.cai@univie.ac.at
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD032100
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD032100

PRIDE project URI

Repository Record List

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